化學(xué)品的健康效應(yīng)涉及外源性化學(xué)物質(zhì)對(duì)接觸人體的毒害作用表現(xiàn)規(guī)律、敏感檢測指標(biāo)和生物學(xué)標(biāo)志等,直接影響人和環(huán)境中的各種生物,也會(huì)對(duì)測試化學(xué)品危害性的人員造成影響。本書介紹了73個(gè)常用的化學(xué)品健康效應(yīng)測試方法,供有關(guān)方面在對(duì)化學(xué)品進(jìn)行危害性篩查、鑒別和分類時(shí)使用,所得結(jié)果可用來評(píng)價(jià)其對(duì)健康影響和環(huán)境風(fēng)險(xiǎn),以便在研發(fā)、生產(chǎn)、使用、廢棄處置等過程中采取有效措施,最大限度防控其風(fēng)險(xiǎn)。
本書為相關(guān)單位開展化學(xué)品危害性測試和GHS分類、合格實(shí)驗(yàn)室建設(shè)、新化學(xué)物質(zhì)登記及進(jìn)行化學(xué)品風(fēng)險(xiǎn)評(píng)估提供指導(dǎo)和幫助,也可作為化學(xué)品環(huán)境管理專家評(píng)審化學(xué)品危害性測試數(shù)據(jù)和GHS分類報(bào)告、風(fēng)險(xiǎn)評(píng)估報(bào)告,以及進(jìn)行合格實(shí)驗(yàn)室考核的技術(shù)參考。
第一版出版說明
第一版前言
概論:
401急性經(jīng)口毒性試驗(yàn)(Acute Oral Toxicity Test)
402急性經(jīng)皮毒性試驗(yàn)(Acute Dermal Toxicity Test)
403急性吸入毒性試驗(yàn)(Acute Inhalation Toxicity Test)
404急性皮膚刺激性/腐蝕性試驗(yàn)(Acute Dermal Irritation/Corrosion Test)
405急性眼刺激性/腐蝕性試驗(yàn)(Acute Eye Irritation/Corrosion Test)
406皮膚致敏試驗(yàn)(Skin Sensitization Test):
407嚙齒類動(dòng)物重復(fù)染毒28天經(jīng)口毒性試驗(yàn) (Repeated Dose 28·day OralToxicity Study in Rodents)
408嚙齒類動(dòng)物亞慢性(90天)經(jīng)口毒性試驗(yàn) (Repeated Dose 90-day OralToxicity in Rodents)
序言
序
第二版出版說明
第二版前言
第一版出版說明
第一版前言
概論:
401急性經(jīng)口毒性試驗(yàn)(Acute Oral Toxicity Test)
402急性經(jīng)皮毒性試驗(yàn)(Acute Dermal Toxicity Test)
403急性吸入毒性試驗(yàn)(Acute Inhalation Toxicity Test)
404急性皮膚刺激性/腐蝕性試驗(yàn)(Acute Dermal Irritation/Corrosion Test)
405急性眼刺激性/腐蝕性試驗(yàn)(Acute Eye Irritation/Corrosion Test)
406皮膚致敏試驗(yàn)(Skin Sensitization Test):
407嚙齒類動(dòng)物重復(fù)染毒28天經(jīng)口毒性試驗(yàn) (Repeated Dose 28·day OralToxicity Study in Rodents)
408嚙齒類動(dòng)物亞慢性(90天)經(jīng)口毒性試驗(yàn) (Repeated Dose 90-day OralToxicity in Rodents)
409非嚙齒類動(dòng)物重復(fù)染毒90天經(jīng)口毒性試驗(yàn)(Repeated Dose 90 day Oral Toxicity inNon-Rodents)
410反復(fù)經(jīng)皮毒性:21天或28天試驗(yàn)(Repeated Dose Dermal Toxicity:21/28一dayStudy)
411亞慢性經(jīng)皮毒性:90天試驗(yàn)(Subchronic Dermal Toxicity:90day Study)
412亞急性吸入毒性:28天試驗(yàn)(Subacute Inhalation Toxicity:28一day Study)
413亞慢性吸入毒性:90天試驗(yàn)(Subchronic Inhalation Toxicity:90·day Study)
414孕期發(fā)育毒性試驗(yàn)(Prenatal Developmental Toxicity Study)
415一代繁殖毒性試驗(yàn)(One—Generation Reproduction Toxicity Study)
416兩代繁殖毒性試驗(yàn)(Tw0Generation Reproduction Toxicity Study)
417毒物動(dòng)力學(xué)試驗(yàn)(Toxicokinetics)
418有機(jī)磷化合物急性染毒的遲發(fā)性神經(jīng)毒性試驗(yàn)(Delayed Neurotoxicity of OrganophosphorusSubstances FollowingAcute Exposure)
……
序言
序
第二版出版說明
第二版前言
第一版出版說明
第一版前言
概論:
401急性經(jīng)口毒性試驗(yàn)(Acute Oral Toxicity Test)
402急性經(jīng)皮毒性試驗(yàn)(Acute Dermal Toxicity Test)
403急性吸入毒性試驗(yàn)(Acute Inhalation Toxicity Test)
404急性皮膚刺激性/腐蝕性試驗(yàn)(Acute Dermal Irritation/Corrosion Test)
405急性眼刺激性/腐蝕性試驗(yàn)(Acute Eye Irritation/Corrosion Test)
406皮膚致敏試驗(yàn)(Skin Sensitization Test):
407嚙齒類動(dòng)物重復(fù)染毒28天經(jīng)口毒性試驗(yàn) (Repeated Dose 28·day OralToxicity Study in Rodents)
408嚙齒類動(dòng)物亞慢性(90天)經(jīng)口毒性試驗(yàn) (Repeated Dose 90-day OralToxicity in Rodents)
序言
序
第二版出版說明
第二版前言
第一版出版說明
第一版前言
概論:
401急性經(jīng)口毒性試驗(yàn)(Acute Oral Toxicity Test)
402急性經(jīng)皮毒性試驗(yàn)(Acute Dermal Toxicity Test)
403急性吸入毒性試驗(yàn)(Acute Inhalation Toxicity Test)
404急性皮膚刺激性/腐蝕性試驗(yàn)(Acute Dermal Irritation/Corrosion Test)
405急性眼刺激性/腐蝕性試驗(yàn)(Acute Eye Irritation/Corrosion Test)
406皮膚致敏試驗(yàn)(Skin Sensitization Test):
407嚙齒類動(dòng)物重復(fù)染毒28天經(jīng)口毒性試驗(yàn) (Repeated Dose 28·day OralToxicity Study in Rodents)
408嚙齒類動(dòng)物亞慢性(90天)經(jīng)口毒性試驗(yàn) (Repeated Dose 90-day OralToxicity in Rodents)
409非嚙齒類動(dòng)物重復(fù)染毒90天經(jīng)口毒性試驗(yàn)(Repeated Dose 90 day Oral Toxicity inNon-Rodents)
410反復(fù)經(jīng)皮毒性:21天或28天試驗(yàn)(Repeated Dose Dermal Toxicity:21/28一dayStudy)
411亞慢性經(jīng)皮毒性:90天試驗(yàn)(Subchronic Dermal Toxicity:90day Study)
412亞急性吸入毒性:28天試驗(yàn)(Subacute Inhalation Toxicity:28一day Study)
413亞慢性吸入毒性:90天試驗(yàn)(Subchronic Inhalation Toxicity:90·day Study)
414孕期發(fā)育毒性試驗(yàn)(Prenatal Developmental Toxicity Study)
415一代繁殖毒性試驗(yàn)(One—Generation Reproduction Toxicity Study)
416兩代繁殖毒性試驗(yàn)(Tw0Generation Reproduction Toxicity Study)
417毒物動(dòng)力學(xué)試驗(yàn)(Toxicokinetics)
418有機(jī)磷化合物急性染毒的遲發(fā)性神經(jīng)毒性試驗(yàn)(Delayed Neurotoxicity of OrganophosphorusSubstances FollowingAcute Exposure)
……